West Midlands Ambulance Service was called to Pershore Road South in Birmingham at 6.37am and sent two ambulances, a paramedic officer, a MERIT trauma doctor and the Midlands Air Ambulance Critical Care Car to the scene.
A West Midlands Ambulance Service spokesman said: “On arrival at the scene, crews discovered the lorry driver, a man in his 40s, receiving excellent first aid from bystanders. The patient was outside of his lorry at the time of the collision.
“He received specialist trauma care for multiple injuries he had suffered, including a serious leg injury.
“He was immobilised and given pain relief before being taken to Queen Elizabeth Hospital, Birmingham on blue lights and sirens. The doctor travelled on the back of the ambulance to help continue treatment en-route to hospital.
“The van driver, a man, was treated for minor injuries before being discharged at the scene.”